OU Engineer Aims to Accelerate Development of mRNA Technology Platforms
An engineering researcher at the University of Oklahoma is part of a National Science Foundation project addressing the logistical challenges of maintaining cryogenic temperatures for Messenger RNA (mRNA) molecules, a molecule that allows human cells to recognize and protect against infectious diseases. Dimitrios Papavassiliou , a professor in the School of Chemical, Biological and Materials Engineering in the Gallogly College of Engineering, is investigating Distributed Ribonucleic Acid Manufacturing – DReAM – that would create a manufacturing technique to produce mRNA sequences on demand and on-site. The NSF funds the research through a four-year, $2 million grant from its Emerging Frontiers in Research and Innovation program. “The mRNA molecules are very fragile and require extremely low temperatures for storage and transportation. The DReAM team is working to avoid the need to maintain cryogenic temperatures. We hope our work will revolutionize care for viruses such as HIV, vario